Not known Details About https://www.ceesdekker.net
Not known Details About https://www.ceesdekker.net
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Rotary movement of DNA rotors on nanopores. Prime row: Uncooked video of the Cy5 channel of each rotor. Center row: corresponding single-particle localization effects of each ends on the DNA rotors. The place of the present frame is marked as orange and blue dots, along with the trajectory of the 10 frames in advance of the current body is proven as good traces.
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Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
2007, to start with actual-time detection of strand Trade in homologous recombination by RecA; discovery of the reduced persistence size of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
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Our exploration ranges with the biophysics of DNA to artificial cells and outside of. You should take a look under on the spectrum of our recent assignments.
Quite a few similar developments adopted, where our team established different transistor variants like single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled https://www.ceesdekker.net numerous transistors into tiny proof-of-principle Digital circuits.
Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation
Let's say, rather than applying typical top rated-down silicon electronics, transistors could possibly be built from The underside up using solitary organic molecules as being the switching factors? This concept, which became The premise of right now’s industry of molecular electronics, 1st emerged within the seventies.
At this time, we also realized that it ought to be probable to utilize an individual semiconducting carbon nanotube to generate a transistor — and we set out to really make it. We stretched specific semiconducting nanotubes across metallic electrodes and utilized the underlying silicon substrate to be a gate electrode, creating The fundamental 3-terminal layout of the industry-influence transistor (Fig.
Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
Cees Dekker is Distinguished College Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes inside the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current study focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, especially SMC motor protein; and (iii) creating a residing synthetic cell from lifeless molecules. Dekker can be an elected member of the KNAW and fellow to the APS and the IOP.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
Case in point (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim from the pore is highlighted in crimson, as well as a 3D rendering in the motion from the DNA rod is shown.